I'm running Server 2003 Enterprise x64.
RAID 1 for the system files on C:
RAID 1 for Visual MFG log files on d:
RAID 1 for Sharepoint log files on e:
RAID 5 for the data on f:
My database is almost 8GB now!
I run Visual, Sharepoint 3.0, and Reporting Services on this server with no problem.
I have around 50 concurrent users and 20 barcode stations.
My remote sites connect using Terminal services and thin clients over our WAN.
Update! - Make sure you have a RAID 1 for your TEMPDB databases and you need one TEMPDB file for every 4 cores you have in your CPUs. (So dual Quad Cores would need 2 TempDB files)